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Spatial transcriptomic landscape unveils immunoglobin-associated senescence as a hallmark of aging 期刊论文
CELL, 2024, 卷号: 187, 期号: 24
作者:  Ma, Shuai;  Ji, Zhejun;  Zhang, Bin;  Geng, Lingling;  Cai, Yusheng;  Nie, Chao;  Li, Jiaming;  Zuo, Yuesheng;  Sun, Yuzhe;  Xu, Gang;  Liu, Beibei;  Ai, Jiaqi;  Liu, Feifei;  Zhao, Liyun;  Zhang, Jiachen;  Zhang, Hui;  Sun, Shuhui;  Huang, Haoyan;  Zhang, Yiyuan;  Ye, Yanxia;  Fan, Yanling;  Zheng, Fangshuo;  Hu, Jinghao;  Zhang, Baohu;  Li, Jingyi;  Feng, Xin;  Zhang, Feng;  Zhuang, Yuan;  Li, Tianjie;  Yu, Yang;  Bao, Zhaoshi;  Pan, Sipei;  Esteban, Concepcion Rodriguez;  Liu, Zhili;  Deng, Haohao;  Wen, Feng;  Song, Moshi;  Wang, Si;  Zhu, Guodong;  Yang, Jiayin;  Jiang, Tao;  Song, Weihong;  Belmonte, Juan Carlos Izpisua;  Qu, Jing;  Zhang, Weiqi;  Gu, Ying;  Li, Guang-Hui
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CELLULAR SENESCENCE  SECRETORY PHENOTYPE  CELLS  REPROGRAMS  ATLAS  HISAT  
Metformin decelerates aging clock in male monkeys 期刊论文
CELL, 2024, 卷号: 187, 期号: 22
作者:  Yang, Yuanhan;  Lu, Xiaoyong;  Liu, Ning;  Ma, Shuai;  Zhang, Hui;  Zhang, Zhiyi;  Yang, Kuan;  Jiang, Mengmeng;  Zheng, Zikai;  Qiao, Yicheng;  Hu, Qinchao;  Huang, Ying;  Zhang, Yiyuan;  Xiong, Muzhao;  Liu, Lixiao;  Jiang, Xiaoyu;  Reddy, Pradeep;  Dong, Xueda;  Xu, Fanshu;  Wang, Qiaoran;  Zhao, Qian;  Lei, Jinghui;  Sun, Shuhui;  Jing, Ying;  Li, Jingyi;  Cai, Yusheng;  Fan, Yanling;  Yan, Kaowen;  Jing, Yaobin;  Haghani, Amin;  Xing, Mengen;  Zhang, Xuan;  Zhu, Guodong;  Song, Weihong;  Horvath, Steve;  Esteban, Concepcion Rodriguez;  Song, Moshi;  Wang, Si;  Zhao, Guoguang;  Li, Wei;  Belmonte, Juan Carlos Izpisua;  Qu, Jing;  Zhang, Weiqi;  Liu, Guang-Hui
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HUMAN PLASMA PROTEOME  SOFTWARE  PATHWAY  MORTALITY  PACKAGE  MODELS  IMAGE  
CRISPR screening uncovers nucleolar RPL22 as a heterochromatin destabilizer and senescence driver 期刊论文
NUCLEIC ACIDS RESEARCH, 2024, 页码: 352-352
作者:  Li, Hong-Yu;  Wang, Min;  Jiang, Xiaoyu;  Jing, Yaobin;  Wu, Zeming;  He, Yifang;  Yan, Kaowen;  Sun, Shuhui;  Ma, Shuai;  Ji, Zhejun;  Wang, Si;  Belmonte, Juan Carlos Izpisua;  Qu, Jing;  Zhang, Weiqi;  Wei, Taotao;  Liu, Guang-Hui
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LIFE-SPAN EXTENSION  RIBOSOME BIOGENESIS  STEM-CELLS  RNA  CANCER  TRANSCRIPTION  HOMEOSTASIS  ACTIVATION  KNOCKOUT  SUBUNITS  
CRISPR-based screening pinpoints H2AZ1 as a driver of senescence in human mesenchymal stem cells 期刊论文
PROTEIN & CELL, 2024, 页码: 460-474
作者:  Li, Ming-Heng;  Jiang, Xiaoyu;  Jing, Yaobin;  Yan, Kaowen;  Bi, Shi-Jia;  Wang, Si;  Ma, Shuai;  Liu, Guang-Hui;  Zhang, Weiqi;  Sun, Shuhui;  Qu, Jing
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Single-cell transcriptomic Atlas of aging macaque ocular outflow tissues 期刊论文
PROTEIN & CELL, 2024, 卷号: 15, 期号: 8, 页码: 594-611
作者:  Wu, Jian;  Wang, Chaoye;  Sun, Shuhui;  Ren, Tianmin;  Pan, Lijie;  Liu, Hongyi;  Hou, Simeng;  Wu, Shen;  Yan, Xuejing;  Zhang, Jingxue;  Zhao, Xiaofang;  Liu, Weihai;  Zhu, Sirui;  Wei, Shuwen;  Zhang, Chi;  Jia, Xu;  Zhang, Qi;  Yu, Ziyu;  Zhuo, Yehong;  Zhao, Qi;  Yang, Chenlong;  Wang, Ningli
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TRABECULAR MESHWORK  SENESCENCE  GLAUCOMA  AGE  
Identification of FOXO1 as a geroprotector in human synovium through single-nucleus transcriptomic profiling 期刊论文
PROTEIN & CELL, 2024, 卷号: 15, 期号: 6, 页码: 441-459
作者:  Liu, Feifei;  Lu, Yi;  Wang, Xuebao;  Sun, Shuhui;  Pan, Huize;  Wang, Min;  Wang, Zehua;  Zhang, Weiqi;  Ma, Shuai;  Sun, Guoqiang;  Chu, Qun;  Wang, Si;  Qu, Jing;  Liu, Guang-Hui
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ARTICULAR-CARTILAGE  EXPRESSION  MEDIATOR  CELLS  
CRL2APPBP2-mediated TSPYL2 degradation counteracts human mesenchymal stem cell senescence 期刊论文
SCIENCE CHINA-LIFE SCIENCES, 2024, 卷号: 67, 期号: 3, 页码: 460-474
作者:  Huang, Daoyuan;  Zhao, Qian;  Yang, Kuan;  Lei, Jinghui;  Jing, Ying;  Li, Hongyu;  Zhang, Chen;  Ma, Shuai;  Sun, Shuhui;  Cai, Yusheng;  Wang, Guibin;  Qu, Jing;  Zhang, Weiqi;  Wang, Si;  Liu, Guang-Hui
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UBIQUITIN  CDA1  PROLIFERATION  HOMEOSTASIS  ACTIVATION  INHIBITOR  APOPTOSIS  MLN4924  ENZYME  BETA  
Aging induces region-specific dysregulation of hormone synthesis in the primate adrenal gland 期刊论文
NATURE AGING, 2024, 卷号: 4, 期号: 3
作者:  Wang, Qiaoran;  Wang, Xuebao;  Liu, Beibei;  Ma, Shuai;  Zhang, Feng;  Sun, Shuhui;  Jing, Yaobin;  Fan, Yanling;  Ding, Yingjie;  Xiong, Muzhao;  Li, Jiaming;  Zhai, Qiaocheng;  Zheng, Yandong;  Liu, Chengyu;  Xu, Gang;  Yang, Jiayin;  Wang, Si;  Ye, Jinlin;  Belmonte, Juan Carlos Izpisua;  Qu, Jing;  Liu, Guang-Hui;  Zhang, Weiqi
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DEHYDROEPIANDROSTERONE-SULFATE  GENE-EXPRESSION  STEROIDOGENESIS  BIOMARKER  ZONATION  HUMANS  FAMILY  
A single-nucleus transcriptomic atlas of primate liver aging uncovers the pro-senescence role of SREBP2 in hepatocytes 期刊论文
PROTEIN & CELL, 2024, 卷号: 15, 期号: 2, 页码: 98-120
作者:  Yang, Shanshan;  Liu, Chengyu;  Jiang, Mengmeng;  Liu, Xiaoqian;  Geng, Lingling;  Zhang, Yiyuan;  Sun, Shuhui;  Wang, Kang;  Yin, Jian;  Ma, Shuai;  Wang, Si;  Belmonte, Juan Carlos Izpisua;  Zhang, Weiqi;  Qu, Jing;  Liu, Guang-Hui
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AGE-RELATED-CHANGES  SPECIES-DIFFERENCES  STELLATE CELLS  TGF-BETA  CHOLESTEROL  PATHOPHYSIOLOGY  MAINTENANCE  HOMEOSTASIS  METABOLISM  PHYSIOLOGY  
Database Resources of the National Genomics Data Center,China National Center for Bioinformation in 2022 期刊论文
NUCLEIC ACIDS RESEARCH, 2022, 卷号: 50, 页码: 27-38
作者:  Xue Yongbiao;  Bao Yiming;  Zhang Zhang;  Zhao Wenming;  Xiao Jingfa;  He Shun-min;  Zhang Guoqing;  Li Yixue;  Guoping Zhao;  Chen Runsheng;  Zeng Jingyao;  Zhang Yadong;  Shang Yun-fei;  Mai Jialin;  Shi Shuo;  Lu Mingming;  Bu Congfan;  Zhang Zhewen;  Du Zhenglin;  Wang Yinying;  Kang Hongen;  Xu Tianyi;  Hao Lili;  Jia Peilin;  Jiang Shuai;  Qian Qiheng;  Zhu Tong-tong;  Shang Yunfei;  Zong Wenting;  Jin Tong;  Zhang Yuansheng;  Zou Dong;  Zhang Zhang;  Du Qiang;  Feng Changrui;  Ma Lina;  Zhang Sisi;  Wang Anke;  Dong Lili;  Wang Yan-qing;  Liu Wan;  Yan Xing;  Ling Yunchao;  Zhao Guoping;  Zhou Zhihua;  Kang Wang;  Zhang Tao;  Ma Shuai;  Yan Haoteng;  Liu Zunpeng;  Ji Zejun;  Cai Yusheng;  Wang Si;  Song Moshi;  Ren Jie;  Zhou Qi;  Qu Jing;  Zhang Weiqi;  Liu Guanghui;  Chen Xu;  Chen Tingting;  Sisi Zhang;  Sun Yanling;  Yu Caixia;  Tang Bixia;  Zhu Junwei;  Zhai Shuang;  Sun Yubin;  Chen Qiancheng;  Yang Xiaoyu;  Zhang Xin;  Sang Zhengqi;  Wang Yonggang;  Zhao Yilin;  Chen Huanxin;  Lan Li;  Wang Yanqing;  Ma Yingke;  Jia Yaokai;  Zheng Xin-chang;  Chen Meili;  Dong Zou;  Zhu Tongtong;  Ming Chen;  Niu Guangyi;  Pan Rong;  Jing Wei;  Sang Jian;  Liu Chang;  Xiong Yujia;  Lili Hao;  Zhang Mochen;  Wang Guoliang;  Yi Lizhi;  Wei Zhao;  Zong Wenting;  Wu Song;  Xiong Zhuang;  Rujiao Li;  Zheng Gong;  Li Rujiao;  Liu Lin;  Li Zhao;  Li Qianpeng;  Wei Jing;  Luo Sicheng;  Wang Jiajia;  Shi Yirong;  Zhou Honghong;  Zhang Peng;  Song Tingrui;  Li Yanyan;  Yang Fei;  Li Mengwei;  Li Zhao-hua;  Kang Hongen;  Zheng Xinchang;  Li Ru-jiao;  Tian Dongmei;  Liu Xiaonan;  Li Cuiping;  Teng Xufei;  Song Shuhui;  Zhang Yang;  Niu Guangyi;  Zhu Tongtong;  Zhang Yuansheng;  Chen Ruru;  Zhang Rongqin;  Xu Feng;  Wang Yifan;  Ling Yunchao;  Zhou Chenfen;  Wang Haizhou;  Teschendorff Andrew E.;  He Yungang;  Zhen Yang;  Li Cuiping;  Zhu Junwei;  Li Lun;  Li Na;  Gong Zheng;  Chen Meili;  Ying Cui;  Duan Guangya;  Tong Jin;  Wu Gangao;  Huang Tianhao;  Jin Enhui;  Zhao Wei;  Kang Hailong;  Wang Zhonghuang;  Zeng Jingyao;  Chen Hua;  Li Mingkun;  Zhao Wenming;  Ning Wanshan;  Xue Yu;  Liu Yanhu;  Cui Ying;  Zhou Qijun;  Liu Xingyan;  Zhang Longlong;  Mao Bingyu;  Zhang Shihua;  Zhang Yaping;  Wang Guodong;  Zhu Qianghui;  Li Xin;  Li Menghua;  Liu Yuanming;  Luo Hong;  Wu Xiaoyuan;  Jing Haichun;  Pan Yitong;  Chen Ming;  Ma Lina;  Shi Leisheng;  Li Mingkun;  Lan Li;  Bao Yiming;  Zhao Wen-ming;  Zuo Zhixiang;  Ren Jian;  Zhang Xinxin;  Xiao Yun;  Li Xia;  Liu Dan;  Zhang Chi;  Xue Yu;  Zhao Zheng;  Jiang Tao;  Wu Wanying;  Zhao Fangqing;  Meng Xianwen;  Peng Di;  Luo Hao;  Gao Feng;  Lin Shaofeng;  Liu Chuijie;  Guo Anyuan;  Yuan Hao;  Su Tianhan;  Zhang Yong E.;  Zhou Yincong;  Zhang Weizhi;  Fu Shanshan;  Tan Xiaodan;  Xie Yubin;  Guo Guoji;  Wang Chenwei;  Liao Xingyu;  Ga, Xin;  Wang Jianxin;  Xie Guiyan;  Yuan Chunhui;  Tian Feng;  Yang Dechang;  Tang Dachao;  Wu Wenyi;  Gou Yujie;  Han Cheng;  Cui Qinghua;  Li Xiang Shang;  Li Chuan-Yun;  Luo XiaoTong;  Ren Jia;  Li Xia
浏览  |  Adobe PDF(1112Kb)  |  收藏  |  浏览/下载：3123/470  |  提交时间：2023/04/17