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A pig model carrying heterozygous point mutation of NCSTN simulates familial acne inversa and reveals dysregulated cholesterol biosynthesis via the Notch-pAMPK-HMGCR pathway 期刊论文
SCIENCE BULLETIN, 2021, 卷号: 66, 期号: 23, 页码: 2343-2346
作者:  Song RG(宋瑞高);  Liu KQ(刘克强);  Wang Y(王煜);  Qin GS(秦国嵩);  Xiao M(肖萌);  Liu YP(刘雅萍);  Yang J(杨俊);  Zong RJ(宗若君);  Yan XH(闫星彗);  Zheng QT(郑千涛);  Zhang HY(张洪勇);  Hou NP(侯乃鹏);  Yao J(姚婧);  Wang X(王霄);  Wang YF(王彦芳);  Zhao JG(赵建国);  Zhang X(张学)
Adobe PDF(1650Kb)  |  收藏  |  浏览/下载：202/95  |  提交时间：2023/04/17
Reconstitution of UCP1 Using CRISPR/Cas9 in the White Adipose Tissue of Pigs Decreases Fat Deposition and Improves Thermogenic Capacity 期刊论文
PNAS, 2017, 卷号: 114, 期号: 45, 页码: E9474-E9482
作者:  Zheng QT(郑千涛);  Lin J(林骏);  Huang JJ(黄娇娇);  Zhang HY(张洪勇);  Zhang R(张蕊);  Xue-Ying Zhang;  Cao CW(曹春伟);  Catherine Hambly;  Qin GS(秦国嵩);  Yao J(姚婧);  Song RG(宋瑞高);  Jia QT(贾启涛);  Wang X(王霄);  Yong-Shun Li;  Zhang N(张楠);  Zheng-Yu Piao;  Ye RC(叶荣财);  John R.Speakman;  Wang HM(王红梅);  Zhou Q(周琪);  Wang YF(王彦芳);  Jin WZ(金万洙);  Zhao JG(赵建国)
Adobe PDF(1304Kb)  |  收藏  |  浏览/下载：619/192  |  提交时间：2018/07/09
Reconstitution of UCP1 Using CRISPR/Cas9 in the White Adipose Tissue of Pigs Decreases Fat Deposition and Improves Thermogenic Capacity 期刊论文
PNAS, 2017, 卷号: 114, 期号: 45, 页码: E9474-E9482
作者:  Zheng QT(郑千涛);  Lin J(林骏);  Huang JJ(黄娇娇);  Zhang HY(张洪勇);  Zhang R(张蕊);  Xue-Ying Zhang;  Cao CW(曹春伟);  Catherine Hambly;  Qin GS(秦国嵩);  Yao J(姚婧);  Song RG(宋瑞高);  Jia QT(贾启涛);  Wang X(王霄);  Yong-Shun Li;  Zhang N(张楠);  Zheng-Yu Piao;  Ye RC(叶荣财);  John R.Speakman;  Wang HM(王红梅);  Zhou Q(周琪);  Wang YF(王彦芳);  Jin WZ(金万洙);  Zhao JG(赵建国)
Adobe PDF(1304Kb)  |  收藏  |  浏览/下载：450/160  |  提交时间：2018/07/09
One-Step Generation of Triple Gene-Targeted Pigs Using CRISPR/Cas9 System 期刊论文
Scientific Reports, 2016, 卷号: 6, 页码: Article No. 20620
作者:  Wang XL(王宪龙);  Cao CW(曹春伟);  Huang JJ(黄娇娇);  Yao J(姚婧);  Hai T(海棠);  Zheng QT(郑千涛);  Wang X(王霄);  Zhang HY(张洪勇);  Qin GS(秦国嵩);  Jin-Bo Cheng;  Wang YF(王彦芳);  Yuan ZQ(袁增强);  Zhou Q(周琪);  Wang HM(王红梅);  Zhao JG(赵建国)
Adobe PDF(1112Kb)  |  收藏  |  浏览/下载：368/133  |  提交时间：2017/07/06