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CRISPR/CAS9-MEDIATED CORRECTION OF MITF HOMOZYGOUS POINT MUTATION IN A WAARDENBURG SYNDROME 2A PIG MODEL 期刊论文
Molecular Therapy-nucleic Acids, 2021, 卷号: 24, 页码: 986-999
Authors:  Yao Jing;  Wang Yu;  Cao Chunwei;  Song Ruigao;  Bi Dengfeng;  Zhang Hongyong;  Li Yongshun;  Qin Guosong;  Hou Naipeng;  Zhang Nan;  Zhang Jin;  Guo Weiwei;  Yang Shiming;  Wang Yanfang;  Zhao Jianguo
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CRISPR/CAS13D-MEDIATED EFFICIENT KDM5B MRNA KNOCKDOWN IN PORCINE SOMATIC CELLS AND PARTHENOGENETIC EMBRYOS 期刊论文
RepRoduction, 2021, 卷号: 162, 期号: 2, 页码: 149-160
Authors:  Bi Dengfeng;  Yao Jing;  Wang Yu;  Qin Guosong;  Zhang Yunting;  Wang Yanfang;  Zhao Jianguo
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A pig model carrying heterozygous point mutation of NCSTN simulates familial acne inversa and reveals dysregulated cholesterol biosynthesis via the Notch-pAMPK-HMGCR pathway 期刊论文
SCIENCE BULLETIN, 2021, 卷号: 66, 期号: 23, 页码: 2343-2346
Authors:  Song RG(宋瑞高);  Liu KQ(刘克强);  Wang Y(王煜);  Qin GS(秦国嵩);  Xiao M(肖萌);  Liu YP(刘雅萍);  Yang J(杨俊);  Zong RJ(宗若君);  Yan XH(闫星彗);  Zheng QT(郑千涛);  Zhang HY(张洪勇);  Hou NP(侯乃鹏);  Yao J(姚婧);  Wang X(王霄);  Wang YF(王彦芳);  Zhao JG(赵建国);  Zhang X(张学)
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Cytosine Base Editor (hA3A-BE3-NG)-Mediated Multiple Gene Editing for Pyramid Breeding in Pigs 期刊论文
FRONTIERS IN GENETICS, 2020, 卷号: 11, 页码: 534-545
Authors:  Wang Y(王宇);  bi dengfeng;  Qin GS(秦国嵩);  song ruigao;  Yao J(姚婧);  Cao Chunwei;  Zheng Qiantao;  Hou Naipeng;  Wang Yanfang;  Zhao JG(赵建国)
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RepSox Increases Porcine Cloning Efficiency by Improving Pluripotency of Donor Nuclei 期刊论文
CELLULAR REPROGRAMMING, 2019, 卷号: 21, 期号: 4, 页码: 181-186
Authors:  Qin GS(秦国嵩);  Zhao JG(赵建国);  Huang JJ(黄娇娇)
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An exonic splicing enhancer mutation in DUOX2 causes aberrant alternative splicing and severe congenital hypothyroidism in Bama pigs 期刊论文
Disease Models & Mechanisms, 2019, 卷号: 12, 期号: 1, 页码: 1-8
Authors:  Cao CW(曹春伟);  Zhang Y(张颖);  Jia QT(贾启涛);  Wang X(王霄);  Zheng QT(郑千涛);  Zhang HY(张洪勇);  Song RG(宋瑞高);  Li YS(李永顺);  Luo AL(罗霭玲);  Hong QL(洪潜龙);  Qin GS(秦国嵩);  Yao J(姚婧);  Zhang N(张楠);  Wang YF(王彥芳);  Wang HM(王红梅);  Zhou Q(周琪);  Zhao JG(赵建国)
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A harlequin ichthyosis pig model with a novel ABCA12mutation can be rescued by acitretin treatment 期刊论文
Journal of Molecular Cell Biology, 2019, 卷号: 11, 期号: 12, 页码: 1029-1041
Authors:  Wang X(王霄);  Cao CW(曹春伟);  Li YS(李永顺);  Hai T(海棠);  Jia QT(贾启涛);  Zhang Y(张颖);  Zheng QT(郑千涛);  Yao J(姚婧);  Qin GS(秦国嵩);  Zhang HY(张洪勇);  Song RG(宋瑞高);  Wang YF(王彥芳);  Guanghou Shui;  Sin Man Lam;  Liu ZH(刘忠华);  Wei H(魏泓);  Meng AM(孟安明);  Zhou Q(周琪);  Zhao JG(赵建国)
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Rescuing ocular development in an anophthalmic pig by blastocyst complementation 期刊论文
EMBO Molecular Medicine, 2018, 期号: doi: 10.15252/emmm.201808861, 页码: 10; e8861:1-12
Authors:  Zhang HY(张洪勇);  Huang JJ(黄娇娇);  Li ZC(李泽辰);  Qin GS(秦国嵩);  Zhang N(张楠);  Hai T(海棠);  Hong QL(洪潜龙);  Zheng QT(郑千涛);  Zhang Y(张颖);  Song RG(宋瑞高);  Yao J(姚婧);  Cao CW(曹春伟);  Zhao JG(赵建国);  Zhou Q(周琪)
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Pilot Study of Large-Scale Production of Mutant Pigs by ENU Mutagenesis 期刊论文
eLife, 2017, 卷号: 6, 页码: Article No. e26248
Authors:  Hai T(海棠);  Cao CW(曹春伟);  Hai-Tao Shang;  Wei-Wei Guo;  Yan-Shuang Mu;  Yang SL(杨述林);  Zhang Y(张颖);  Zheng QT(郑千涛);  Tao Zhang;  Wang XL(王宪龙);  Yu Liu;  Qing-Ran Kong;  Li K(李奎);  Wang DY(王大愚);  Qi M(祁蒙);  Hong QL(洪潜龙);  Zhang R(张蕊);  Wang XP(王秀鹏);  Jia QT(贾启涛);  Wang X(王霄);  Qin GS(秦国嵩);  Yong-Shun Li;  Luo AL(罗霭玲);  Wei-Wu Jin;  Yao J(姚婧);  Huang JJ(黄娇娇);  Zhang HY(张洪勇);  Li MH(李孟华);  Xiang-Mo Xie;  Xue-Juan Zheng;  Ke-Nan Guo;  Gu WW(顾为望);  Ming Li;  Yong Wang;  Wang HM(王红梅);  Yang SM(杨仕明);  Liu ZH(刘忠华);  Wei H(魏泓);  Zhao JG(赵建国);  Zhou Q(周琪);  Meng AM(孟安明)
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Reconstitution of UCP1 Using CRISPR/Cas9 in the White Adipose Tissue of Pigs Decreases Fat Deposition and Improves Thermogenic Capacity 期刊论文
PNAS, 2017, 卷号: 114, 期号: 45, 页码: E9474-E9482
Authors:  Zheng QT(郑千涛);  Lin J(林骏);  Huang JJ(黄娇娇);  Zhang HY(张洪勇);  Zhang R(张蕊);  Xue-Ying Zhang;  Cao CW(曹春伟);  Catherine Hambly;  Qin GS(秦国嵩);  Yao J(姚婧);  Song RG(宋瑞高);  Jia QT(贾启涛);  Wang X(王霄);  Yong-Shun Li;  Zhang N(张楠);  Zheng-Yu Piao;  Ye RC(叶荣财);  John R.Speakman;  Wang HM(王红梅);  Zhou Q(周琪);  Wang YF(王彦芳);  Jin WZ(金万洙);  Zhao JG(赵建国)
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