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A pig model carrying heterozygous point mutation of NCSTN simulates familial acne inversa and reveals dysregulated cholesterol biosynthesis via the Notch-pAMPK-HMGCR pathway 期刊论文
SCIENCE BULLETIN, 2021, 卷号: 66, 期号: 23, 页码: 2343-2346
作者:  Song RG(宋瑞高);  Liu KQ(刘克强);  Wang Y(王煜);  Qin GS(秦国嵩);  Xiao M(肖萌);  Liu YP(刘雅萍);  Yang J(杨俊);  Zong RJ(宗若君);  Yan XH(闫星彗);  Zheng QT(郑千涛);  Zhang HY(张洪勇);  Hou NP(侯乃鹏);  Yao J(姚婧);  Wang X(王霄);  Wang YF(王彦芳);  Zhao JG(赵建国);  Zhang X(张学)
浏览  |  Adobe PDF(1650Kb)  |  收藏  |  浏览/下载：182/86  |  提交时间：2023/04/17
Tubulin detyrosination promotes human trophoblast syncytium formation 期刊论文
J Mol Cell Biol, 2019, 卷号: 11, 期号: 11, 页码: 967-978
作者:  Wang R(王蕊);  Yu RX(于偌萱);  Zhu C(祝诚);  Lin HY(林海燕);  Lv XY(吕晓寅);  Wang HM(王红梅)
浏览  |  Adobe PDF(152674Kb)  |  收藏  |  浏览/下载：210/62  |  提交时间：2020/11/17
A fully defined static suspension culture system for large-scale human embryonic stem cell production 期刊论文
Cell Death & Disease, 2018, 卷号: 9, 期号: 9, 页码: 1-9
作者:  Li X(李夏);  Ma RY(马若昱);  Gu Q(顾奇);  Liang LM(梁灵敏);  Wang L(王磊);  Zhang Y(张映);  Wang XN(王宪宁);  Li ZW(李仲文);  Fang JH(方金辉);  Wu J(吴骏);  Wang YK(王昱凯);  Li W(李伟);  Hu BY(胡宝洋);  Wang L(王柳);  Zhou Q(周琪);  Hao J(郝捷)
浏览  |  Adobe PDF(1643Kb)  |  收藏  |  浏览/下载：402/157  |  提交时间：2019/10/14
Visualization of Aging-Associated Chromatin Alterations with an Engineered TALE System 期刊论文
Cell Research, 2017, 卷号: 27, 期号: 4, 页码: 483-504
作者:  Ruo-Tong Ren;  Li-Ping Deng;  Yan-Hong Xue;  Keiichiro Suzuki;  Wei-Qi Zhang;  Yang Yu;  Jun Wu;  Liang Sun;  Xiao-Jun Gong;  Hui-Qin Luan;  Fan Yang;  Zhen-Yu Ju;  Xiao-Qing Ren;  Si Wang;  Hong Tang;  Ling-Ling Geng;  Wei-Zhou Zhang;  Jian Li;  Qiao J(乔杰);  Xu T(徐涛);  Qu J(曲静);  Liu GH(刘光慧)
浏览  |  Adobe PDF(11674Kb)  |  收藏  |  浏览/下载：375/127  |  提交时间：2018/07/09
Modeling Xeroderma Pigmentosum Associated Neurological Pathologies with Patients-Derived iPSCs 期刊论文
Protein & Cell, 2016, 卷号: 7, 期号: 3, 页码: 210-221
作者:  Li-Na Fu;  Xiu-Ling Xu;  Ruo-Tong Ren;  Jun Wu;  Wei-Qi Zhang;  Ji-Ping Yang;  Xiao-Qing Ren;  Si Wang;  Yang Zhao;  Liang Sun;  Yang Yu;  Zhao-Xia Wang;  Ze Yang;  Yun Yuan;  Jie Qiao;  Juan Carlos Izpisua Belmonte;  Qu J(曲静);  Liu GH(刘光慧)
浏览  |  Adobe PDF(3822Kb)  |  收藏  |  浏览/下载：314/75  |  提交时间：2017/07/06
SIRT6 Safeguards Human Mesenchymal Stem Cells from Oxidative Stress by Coactivating NRF2 期刊论文
Cell Research, 2016, 卷号: 26, 期号: 2, 页码: 190-205
作者:  Hui-Ze Pan;  Di Guan;  Xiao-Meng Liu;  Jing-Yi Li;  Li-Xia Wang;  Jun Wu;  Jun-Zhi Zhou;  Wei-Zhou Zhang;  Ruo-Tong Ren;  Wei-Qi Zhang;  Ying Li;  Ji-Ping Yang;  Ying Hao;  Ting-Ting Yuan;  Guo-Hong Yuan;  Hu Wang;  Zhen-Yu Ju;  Zhi-Yong Mao;  Jian Li;  Qu J(曲静);  Tang FC(汤富酬);  Liu GH(刘光慧)
浏览  |  Adobe PDF(6193Kb)  |  收藏  |  浏览/下载：406/173  |  提交时间：2017/07/06
A Werner Syndrome Stem Cell Model Unveils Heterochromatin Alterations as a Driver of Human Aging 期刊论文
Science, 2015, 卷号: 348, 期号: 6239, 页码: 1160-1163
作者:  Wei-Qi Zhang;  Jing-Yi Li;  Keiichiro Suzuki;  Qu J(曲静);  Ping Wang;  Jun-Zhi Zhou;  Xiao-Meng Liu;  Ruo-Tong Ren;  Xiu-Ling Xu;  Alejandro Ocampo;  Ting-Ting Yuan;  Ji-Ping Yang;  Ying Li;  Liang Shi;  Dee Guan;  Hui-Ze Pan;  Shun-Lei Duan;  Zhi-Chao Ding;  Mo Li;  Fei Yi;  Rui-Jun Bai;  Ya-Yu Wang;  Chang Chen;  Fu-Quan Yang;  Xiao-Yu Li;  Zi-Mei Wang;  Emi Aizawa;  April Goebl;  Rupa Devi Soligalla;  Pradeep Reddy;  Concepcion Rodriguez Esteban;  Tang FC(汤富酬);  Liu GH(刘光慧);  Juan Carlos Izpisua Belmonte
浏览  |  Adobe PDF(1362Kb)  |  收藏  |  浏览/下载：487/174  |  提交时间：2016/06/14
A Widely Adaptable Approach to Generate Integration-Free iPSCs from Non-Invasively Acquired Human Somatic Cells 期刊论文
Protein & Cell, 2015, 卷号: 6, 期号: 5, 页码: 386-389
作者:  Zhi-Chao Ding;  Li-Na Sui;  Ruo-Tong Ren;  Yan-Jun Liu;  Xiu-Ling Xu;  Li-Na Fu;  Rui-Jun Bai;  Ting-Ting Yuan;  Ying Hao;  Wei-Qi Zhang;  Hui-Ze Pan;  Wen-Su Liu;  Han Yu;  Concepcion Rodriguez Esteban;  Xiao-Bing Yu;  Ze Yang;  Jian Li;  Xiao-Min Wang;  Juan Carlos Izpisua Belmonte;  Liu GH(刘光慧);  Fei Yi;  Qu J(曲静)
浏览  |  Adobe PDF(826Kb)  |  收藏  |  浏览/下载：388/123  |  提交时间：2016/06/14