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| A pig model carrying heterozygous point mutation of NCSTN simulates familial acne inversa and reveals dysregulated cholesterol biosynthesis via the Notch-pAMPK-HMGCR pathway 期刊论文
SCIENCE BULLETIN, 2021, 卷号: 66, 期号: 23, 页码: 2343-2346
作者: Song RG(宋瑞高); Liu KQ(刘克强); Wang Y(王煜); Qin GS(秦国嵩); Xiao M(肖萌); Liu YP(刘雅萍); Yang J(杨俊); Zong RJ(宗若君); Yan XH(闫星彗); Zheng QT(郑千涛); Zhang HY(张洪勇); Hou NP(侯乃鹏); Yao J(姚婧); Wang X(王霄); Wang YF(王彦芳); Zhao JG(赵建国); Zhang X(张学)
 浏览 |  Adobe PDF(1650Kb) |  收藏 | 浏览/下载：181/86 | 提交时间：2023/04/17 |
| Phase I study of CRISPR-engineered CAR-T cells with PD-1 inactivation in treating mesothelin-positive solid tumors 期刊论文
JOURNAL OF CLINICAL ONCOLOGY, 2020, 卷号: 38, 期号: 15
作者: Wang Zhenguang; Chen Meixia; Zhang Yan; Liu Yang; Yang Qingming; Nie Jing; Shen Lianjun; Jiang Pengfei; He Jiaping; Ye Xun; Cao Wei; Wang HY(王皓毅); Han Weidong
浏览 | Adobe PDF(454Kb) | 收藏 | 浏览/下载：325/135 | 提交时间：2021/10/26 |
| TGF-beta inhibition via CRISPR promotes the long-term efficacy of CAR T cells against solid tumors 期刊论文
JCI INSIGHT, 2020, 卷号: 5, 期号: 4
作者: Tang N(唐娜); Cheng Chen; Zhang Xingying; Qiao Miaomiao; Li Na; Mu Wei; Wei Xiao-Fei; Han Weidong; Wang HY(王皓毅)
浏览 | Adobe PDF(11792Kb) | 收藏 | 浏览/下载：214/83 | 提交时间：2021/10/26 |
| Overcoming Autocrine FGF Signaling-Induced Heterogeneity in Naive Human ESCs Enables Modeling of Random X Chromosome Inactivation 期刊论文
CELL STEM CELL, 2020, 卷号: 27, 期号: 3
作者: An Chenrui; Feng GH(冯桂海); Zhang Jixiang; Cao Shiwei; Wang Ying; Wang Nannan; Lu Falong; Zhou Q(周琪); Wang HY(王皓毅)
浏览 | Adobe PDF(6265Kb) | 收藏 | 浏览/下载：289/126 | 提交时间：2021/10/26 |
| Bacteria-free minicircle DNA system to generate integration-free CAR-T cells 期刊论文
Journal of Medical Genetics, 2019, 卷号: 56, 期号: 1, 页码: 10-17
作者: Cheng C(程晨); Tang N(唐娜); Li JX(李佳鑫); Cao SW(操时伟); Zhang TT(张童童); Xiaofei Wei; Wang HY(王皓毅)
浏览 | Adobe PDF(4322Kb) | 收藏 | 浏览/下载：335/165 | 提交时间：2020/11/17 |
| Argonaute proteins from human gastrointestinal bacteria catalyze DNAguided cleavage of single- and doublestranded DNA at 37 °C 期刊论文
Cell Discovery, 2019, 卷号: 5, 期号: 38, 页码: 1-4
作者: Yuanwei Cao; Sun W(孙文); Jinfeng Wang; Gang Sheng; Guanghai Xiang; Tongtong Zhang; Wenyu Shi; Chun Li; Yanli Wang; Fangqing Zhao; Wang HY(王皓毅)
浏览 | Adobe PDF(786Kb) | 收藏 | 浏览/下载：299/143 | 提交时间：2020/11/17 |
| An exonic splicing enhancer mutation in DUOX2 causes aberrant alternative splicing and severe congenital hypothyroidism in Bama pigs 期刊论文
Disease Models & Mechanisms, 2019, 卷号: 12, 期号: 1, 页码: 1-8
作者: Cao CW(曹春伟); Zhang Y(张颖); Jia QT(贾启涛); Wang X(王霄); Zheng QT(郑千涛); Zhang HY(张洪勇); Song RG(宋瑞高); Li YS(李永顺); Luo AL(罗霭玲); Hong QL(洪潜龙); Qin GS(秦国嵩); Yao J(姚婧); Zhang N(张楠); Wang YF(王彥芳); Wang HM(王红梅); Zhou Q(周琪); Zhao JG(赵建国)
浏览 | Adobe PDF(1234Kb) | 收藏 | 浏览/下载：304/111 | 提交时间：2020/11/17 |
| A novel porcine model reproduces human oculocutaneous albinism type II 期刊论文
Cell Discovery, 2019, 卷号: 5, 期号: 1, 页码: 1-3
作者: Zhang Y(张颖); Hong QL(洪潜龙); Cao CW(曹春伟); Yang LZ(杨丽珠); Li YS(李永顺); Hai T(海棠); Zhang HY(张洪勇); Zhou Q(周琪); Sui RF(睢瑞芳); Zhao JG(赵建国)
浏览 | Adobe PDF(766Kb) | 收藏 | 浏览/下载：304/121 | 提交时间：2020/11/17 |
| A harlequin ichthyosis pig model with a novel ABCA12mutation can be rescued by acitretin treatment 期刊论文
Journal of Molecular Cell Biology, 2019, 卷号: 11, 期号: 12, 页码: 1029-1041
作者: Wang X(王霄); Cao CW(曹春伟); Li YS(李永顺); Hai T(海棠); Jia QT(贾启涛); Zhang Y(张颖); Zheng QT(郑千涛); Yao J(姚婧); Qin GS(秦国嵩); Zhang HY(张洪勇); Song RG(宋瑞高); Wang YF(王彥芳); Guanghou Shui; Sin Man Lam; Liu ZH(刘忠华); Wei H(魏泓); Meng AM(孟安明); Zhou Q(周琪); Zhao JG(赵建国)
浏览 | Adobe PDF(104496Kb) | 收藏 | 浏览/下载：280/67 | 提交时间：2020/11/17 |
| Rescuing ocular development in an anophthalmic pig by blastocyst complementation 期刊论文
EMBO Molecular Medicine, 2018, 期号: doi: 10.15252/emmm.201808861, 页码: 10; e8861：1-12
作者: Zhang HY(张洪勇); Huang JJ(黄娇娇); Li ZC(李泽辰); Qin GS(秦国嵩); Zhang N(张楠); Hai T(海棠); Hong QL(洪潜龙); Zheng QT(郑千涛); Zhang Y(张颖); Song RG(宋瑞高); Yao J(姚婧); Cao CW(曹春伟); Zhao JG(赵建国); Zhou Q(周琪)
浏览 | Adobe PDF(3390Kb) | 收藏 | 浏览/下载：426/163 | 提交时间：2019/10/14 |
